"Nanobiosensors design and applications in diagnostics"
Arben Merkoçi
ICN2 - Catalan Institute of Nonoscience and Nanotechnology, Autonomous University of Barcelona, Spain
There is a high demand to develop innovative
and cost effective devices with interest for health care beside
environment diagnostics, safety and security applications. The
development of such devices is strongly related to new materials and
technologies being nanomaterials and nanotechnology of special role. We
study how new nanomaterials such as nanoparticles, graphene,
nano/micromotors can be integrated in simple sensors thanks to their
advantageous properties. Beside plastic platforms physical, chemical and
mechanical properties of cellulose in both micro and nanofiber-based
networks combined with their abundance in nature or easy to prepare and
control procedures are making these materials of great interest while
looking for cost-efficient and green alternatives for device production
technologies. Both paper and nanopaper-based biosensors are emerging as a
new class of devices with the objective to fulfil the “World Health
Organization” requisites to be ASSURED: affordable, sensitive, specific,
user-friendly, rapid and robust, equipment free and deliverable to
end-users. How to design simple paper-based biosensor architectures? How
to tune their analytical performance upon demand? How one can couple
nanomaterials such as metallic nanoparticles, quantum dots and even
graphene with paper and what is the benefit? How we can make these
devices more robust, sensitive and with multiplexing capabilities? Can
we bring these low cost and efficient devices to places with low
resources, extreme conditions or even at our homes? Which are the
perspectives to link these simple platforms and detection technologies
with mobile communication? I will try to give responses to these
questions through various interesting applications related to protein,
DNA and even contaminants detection all of extreme importance for
diagnostics, environment control, safety and security.